Total RNA sequencing of liquid biopsies

Thursday, March 26, 2020
10:30 AM CET

RNA profiling has emerged as a powerful tool to investigate the biomarker potential of human biofluids. However, despite enormous interest in extracellular nucleic acids, RNA sequencing methods to quantify the total RNA content outside cells are rare.

In this webinar, Jo Vandesompele, PhD - CSO at Biogazelle, discussed the performance of the SMARTer Stranded Total RNA-Seq method and show:

  • Its application to various biofluids and extracellular vesicles
  • Accuracy, precision and sensitivity of the method
  • Diversity of RNA biotypes identified and their heterogeneity among different biofluids
  • Performance data with other sample types: FFPE tissue and single cells

About the Speaker

Jo Vandesompele, PhD

Jo Vandesompele, PhD
CSO, Biogazelle


Jo Vandesompele, PhD is co-founder and Chief Scientific Officer at Biogazelle, a CRO specializing in high-value genomics applications to support pharmaceutical research, clinical trials and diagnostic test development. He is also professor in Functional Cancer Genomics and Applied Bioinformatics at Ghent University, Belgium. He obtained a Master of Science in Bioscience Engineering (1997) and a PhD in Medical Genetics (2002). He is author of more than 250 scientific articles in international journals, including some pioneering publications in the domain of RNA quantification and non-coding RNA. His H-index is 66, with 33 000 citations.

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